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07
Oct

Immunosuppressive activity on the murine immune responses of glycyrol from Glycyrrhiza uralensis via inhibition of calcineurin activity

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This paper is to search for an effective immunosuppressant from Glycyrrhiza uralensis (Licorice, Gan Cao). Our results show the immunosuppressive activity of glycyrol and this activity should be due to its inhibitory effect on CN activity, thereby suppressing IL-2 production and regulating T lymphocytes. Thus, glycyrol could be a candidate for development as a novel immunomodulatory drug.

Immunosuppressive activity on the murine immune responses of glycyrol from Glycyrrhiza uralensis via inhibition of calcineurin activity

Reference:
Jiayu Li1, Ying Tu1, Li Tong, Wen Zhang, Jianquan Zheng, and Qun Wei. (2010). Immunosuppressive activity on the murine immune responses of glycyrol from Glycyrrhiza uralensis via inhibition of calcineurin activity. Pharmaceutical Biology, 2010; 48(10): 1177–1184

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