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Immunosuppressive effects of fish oil and flaxseed oil

Posted by on in Skin Matters
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The omega-6 fatty acids are the predominant polyunsaturated fats. The omega-6 and omega-3 fatty acids are metabolically distinct and have opposing physiologic functions. Animal and human studies support the hypothesis that omega-3 PUFA suppress cell mediated immune responses. The increased omega-6/omega-3 ratio in Western diets most likely contributes to an increased incidence of cardiovascular disease and inflammatory disorders.

Immunosuppressive effects of fish oil and flaxseed oil

Virella G, Fourspring K, Hyman B, Haskill-Stroud R, Long L, Virella I, La Via M, Gross AJ, Lopes-Virella M. (1991). Immunosuppressive effects of fish oil in normal human volunteers: correlation with the in vitro effects of eicosapentanoic acid on human lymphocytes. Clinical Immunology and Immunopathology. 1991 Nov;61(2 Pt 1):161-76.

Park HJ, Park JS, Hayek MG, Reinhart GA, Chew BP. (2011). Dietary fish oil and flaxseed oil suppress inflammation and immunity in cats. Veterinary Immunology and Immunopathology. 2011 Jun 15;141(3-4):301-6. doi: 10.1016/j.vetimm.2011.02.024. Epub 2011 Mar 6.

Simopoulos AP. (2002). Omega-3 fatty acids in inflammation and autoimmune diseases. Journal of the American College of Nutrition. 2002 Dec;21(6):495-505.

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Guest Friday, 19 April 2019