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03
Apr
0

Does high consumption of polyunsaturated fatty (Omega-3, Omega-6, Alpha-linolenic) acids and low consumption of total saturated fats benefit coronary disease?

Posted by on in Skin Matters

Alert_14_iconFrom 1956 to July 2013, there were 32 observational studies (512420 participants) of fatty acids from dietary intake; 17 observational studies (25721 participants) of fatty acid biomarkers; and 27 randomized, controlled trials (105085 participants) of fatty acid supplementation. Current evidence does not clearly support cardiovascular guidelines that encourage high consumption of polyunsaturated fatty acids and low consumption of total saturated fats.

 

 

 

Reference:

Rajiv Chowdhury, Samantha Warnakula, Setor Kunutsor et al. (2014) Association of Dietary, Circulating, and Supplement Fatty Acids With Coronary Risk: A Systematic Review and Meta-analysis. Ann Intern Med. 2014;160:398-406.

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09
Sep
0

Are Organic Foods Safer or Healthier Than Conventional Alternatives? A Systematic Review

Posted by on in Skin Matters

alert_12_iconThe health benefits of organic foods are unclear. To review evidence comparing the health effects of organic and conventional foods. MEDLINE (January 1966 to May 2011), EMBASE, CAB Direct, Agricola, TOXNET, Cochrane Library (January 1966 to May 2009), and bibliographies of retrieved articles. English-language reports of comparisons of organically and conventionally grown food or of populations consuming these foods. 17 studies in humans and 223 studies of nutrient and contaminant levels in foods met inclusion criteria.

 


Reference:
Crystal Smith-Spangler, Margaret L. Brandeau, Grace E. Hunter,  et al.  (2012). Are Organic Foods Safer or Healthier Than Conventional Alternatives? A Systematic Review.  Annals of Internal Medicine. 2012;157:348-366. Continue reading
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12
Jul
0

Immunosuppressive effects of fish oil and flaxseed oil

Posted by on in Skin Matters

Alert_11_iconThe omega-6 fatty acids are the predominant polyunsaturated fats. The omega-6 and omega-3 fatty acids are metabolically distinct and have opposing physiologic functions. Animal and human studies support the hypothesis that omega-3 PUFA suppress cell mediated immune responses. The increased omega-6/omega-3 ratio in Western diets most likely contributes to an increased incidence of cardiovascular disease and inflammatory disorders.


 

Reference:
Virella G, Fourspring K, Hyman B, Haskill-Stroud R, Long L, Virella I, La Via M, Gross AJ, Lopes-Virella M. (1991). Immunosuppressive effects of fish oil in normal human volunteers: correlation with the in vitro effects of eicosapentanoic acid on human lymphocytes. Clinical Immunology and Immunopathology. 1991 Nov;61(2 Pt 1):161-76.

Park HJ, Park JS, Hayek MG, Reinhart GA, Chew BP. (2011). Dietary fish oil and flaxseed oil suppress inflammation and immunity in cats. Veterinary Immunology and Immunopathology. 2011 Jun 15;141(3-4):301-6. doi: 10.1016/j.vetimm.2011.02.024. Epub 2011 Mar 6.

Simopoulos AP. (2002). Omega-3 fatty acids in inflammation and autoimmune diseases. Journal of the American College of Nutrition. 2002 Dec;21(6):495-505.

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12
Jul
0

A Review of Health Outcomes in Patients with Psoriasis

Posted by on in Skin Matters

Alert10_iconPearce and colleagues110 examined the cost-effectiveness of psoriasis treatments over a 12-week period comparing methotrexate, acitretin, cyclosporine, narrow band UV-B, PUVA, etanercept, and efalizumab. The total cost per completed treatment regimen was calculated based on drug acquisition costs, dosing and cost of physician visits, laboratory testing, phototherapy treatment charges, liver biopsy, and infusions charges.

 

 

Reference:
Li Kai & Armstrong April W. (2012). A Review of Health Outcomes in Patients with Psoriasis. Dermatologic Clinics. Volume 30, Issue 1, Pages 61-72, January 2012 Continue reading
Tagged in: Psoriasis
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29
Apr
0

Psoriasis Flare from Koebner’s Phenomenon after Acupuncture

Posted by on in Skin Matters

Alert9_icon

A 73-year-old man who had had plaque psoriasis for more than 20 years on the arms, legs, and scalp presented for consultation on a new rash. He had been using topical steroid creams and shampoos to control occasional psoriatic flares.

 

 

 

Reference:
Jashin J. Wu, Caroline Caperton. (2013). Psoriasis Flare from Koebner’s Phenomenon after Acupuncture. New England Journal of Medicine. 2013; 368:1635April 25, 2013DOI: 10.1056/NEJMicm120571

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Tagged in: Psoriasis
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