
A 50-year-old man presented with cutaneous small vessel vasculitis CSVV 皮肤小血管炎
A 50-year-old otherwise healthy man is present with 10 months of tender skin rashes with mild itch, reddish-brown spots…
Read moreA 50-year-old otherwise healthy man is present with 10 months of tender skin rashes with mild itch, reddish-brown spots…
Read moreA woman, otherwise healthy, in her 50’s, she was examined via online consultation by our clinic with a 3-month…
Read moreA 45-year-old otherwise healthy female was presented with 3 months of flexural psoriasis. Initially, she reported rashes…
Read moreCase Report A 11-year-old boy, with no medical history, was presented with round erythematous pruritic lesions (approximately…
Read moreCase Report A 30-year-old man was presented with reddish maculopapular rash on his face, neck, chest and back. There was…
Read more希波克拉底 Hippocrates (460-377BC) 描述了一组斑块、脱皮、鳞屑的皮肤病症状,可能相当于今天的银屑病或麻风病。400年前,哲学家们放弃了亚里士多德的世界观兴高采烈地接受了牛顿世界观来解释生物学并研究医学病理学。在1841年赫伯拉…
Read moreA 70-year-old retired female physician was presented with elevated bullae fluid-filled blisters on the roof of her mouth…
Read moreA 50-year-old male presented with generalised skin lesions for 12 months. He reported brown rashes appearing on the arms…
Read moreA previously healthy 55-year old woman presented with progressive rash that involved her face that had lasted for 5 years…
Read moreThromboangiitis obliterans, also known as Buerger’s disease, is an inflammatory disease that result in blood clot…
Read moreOn 12 July BMJ published a concerned article about corticosteroids. “Synthetic glucocorticoids are widely used for…
Read moreA 37-year-old otherwise healthy woman presented with a 2 years history of erythema of the face & dry lip sought for…
Read moreA 15-year-old boy had been treated for 10 years for moderate to severe atopic dermatitis. The neck eczema was his main…
Read moreA 70-year-old female presented with a 1-year history of bedsore. On her right greater trochanter and sacrum, two 3cm-diameter…
Read more这是一个令人悲伤的故事。如果你是那个故事里的主角,你能不能突破权威制定的标准化或某种正确思想,或者你敢不敢质疑周围人都觉得理所当然的道理,当大多数人都处在认知误区时,你能拥有跳出来做出改变的勇气吗?每个人对于世界的认知都是片面的,我们都是井底之蛙,区别在于井口的大小。只是我们无法生出改变的勇气,每一个细小的改变都是源于认知的改变,让我们知晓还有更多的可能性。我们愿意选择成为一个会被时间冲淡的故事还是定格时间的传奇?…
Read moreIPhone 12 芯片有125亿颗晶体管,如果损坏,理论上讲无法找出哪一颗出了毛病,所以维修时会把整只芯片换掉。人类细胞核的DNA有30亿碱基对,它们不是人类设计的,不要说哪个错了难以发现,我们对怎样才是正确的都所知甚少。至少计算机科学家知道每一个晶体管是干什么用的,而很多DNA片段是干什么用的,生物学家一无所知。那么什么时候我们会把30亿对怎么用的搞清楚呢?生物学家一定会说,我们以前有一个问题,找到遗传物质基础,解决了一个旧问题后,我们碰到了3万个新问题(3万个基因)。…
Read more一个成人拥有约30万亿个人体细胞,同时拥有40万亿个细菌,这些细菌占我们体重的1%至3%。尽管细菌经常被视为疾病的一种来源,但细菌大多无害甚至有益。我们的肠道生活着500种大约1公斤(100万亿)微生物。它们是人类非同寻常的伙伴,它们雕刻我们的器官,保护我们免受疾病侵害,分解我们的食物,教育我们的免疫系统,指导我们的行为,用其基因轰击我们的基因组,并赋予我们不可思议的能力。…
Read moreA 14-year-old student presented with burn injury due to scalding soup exposure 6 hours prior to proper medical attention….
Read moreFig. 1 | Postoperative Autograft Burn Wound Treatment. A patient with a severe industrial ethanol burn injury had undergone…
Read morePatient happily announced that he is fully recovered, and had requested to disclose his full face for the testimonial….
Read moreA merry heart doeth good like a medicine: but a broken spirit drieth the bones. — KJV Pro 17:22 喜乐的心,乃是良药;…
Read moreFolliculitis is an infammaiton of the superficial or deep hair follicle on hair-bearing skin due to infectious or non-infectious…
Read moreOvernight, keratinocytes (kind of skin epidermis cell) proliferate rapidly, preparing and protecting our outer barrier…
Read more130 years ago, Lord Kelvin asked how space might be partitioned into cells of fixed equal volume with minimum surface…
Read moreSteroid induced Rosacea: persistent facial erythema and inflammatory papulopustules, additional features are facial telangiectasias,…
Read moreEach year, doctors prescribe courses of oral corticosteroids to three quarters of patients with chronic inflammatory disorders…
Read more过敏反应主要和获得性免疫有关。机体对某些抗原物质初次接触以后产生初次免疫应答,此后便有了免疫记忆,当再次接触相同抗原时,就可触发免疫应答或者导致相应的过敏反应。机体从环境当中获取抗原(比如饮食中的一些蛋白质),抗原成分经过抗原递呈细胞,提取抗原信息,刺激调节性T细胞,从而呈递给T辅助细胞,促使T辅助细胞向Th1或者Th2两条途径发展。如果朝着Th2方向发展,就是过敏反应方向。…
Read moreA 54-year-old woman presented with 3 months of facial rash. The rash persisted despite a recent 2-month applicaiton of…
Read moreGlucocorticoids [1] plus the sympathetic nervous system [2] enables an organism to survive a physical stressor by activating…
Read moreA 40-year-old woman presented with a two-month history of worsening rashes on her chest, arms and legs. Twenty months…
Read moreWhat is Corticosteroid Withdrawal Syndrome CWS?Steroids Withdrawal Syndrome is a distinct clinical adverse effect of steroid….
Read more《新英格兰医学杂志》2020年7月9日发表了一篇取名为nemolizumab的生物制剂治疗湿疹的三期临床实验如下:…
Read moreDo we have eczema gene(s) – Time to rethink
Read moreChronic pruritus (itch) is defined as ‘an unpleasant sensation leading to the desire to scratch lasting at least 6 weeks…
Read moreKnow then thyself, presume not God to scan; The proper study of mankind is man. — Alexander Pope, Essay on Man PAST…
Read moreStaphylococcus is a group of Gram-positive cocci. It is named because it appears spherical (cocci) and form in grape-like…
Read moreOur present system of scientific communication depends almost entirely on the “primary” literature. This has three…
Read moreWhat is diabetes mellitus? All the human cells need sugar to work normally. Sugar enters into the cells with the help…
Read moreThe prevalence of immue system related skin disorders such as psoriasis, atopic dermatitis (AD) , and allergy has increased…
Read moreChronic plaque psoriasis is the most common clinical form of psoriasis in children, approximately one-third reported onset…
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