Acute Eczematous Reactions 急性湿疹样反应
We present a patient who developed acute eczematous eruptions with an unknown trigger. This patient was a 13-year-old male with a history of seasonal allergies. He developed pruritic eruptions on his lower limbs since the last 5 days. He has a family history of atopic dermatitis but he has no personal history of atopic dermatitis or any other medical issues. His mother had a history of eczema and was successfully treated by our clinic before.
Patient’s mother reports that the patient received his 2nd dose of the COVID-19 vaccine one month ago. We are unable to establish that if his eczematous flare-up reaction was ascribable to the COVID-19 vaccines. On examination, confluent erythema and papules are present bilaterally on his lower extremities with the formation of crusts and exudate, particularly severe on the right side. He was treated with an oral herbal medicine and topical herbal cream, resolving his symptoms just 5 months. We are grateful towards this patient’s parents for sending us the photos via WeChat and giving us consent for these photos to be used as a testimonial.
一位患者出现了急性湿疹性皮疹,触发因素不明。该患者是一名13岁的男性,有季节性过敏的病史。他在过去5天内出现了下肢瘙痒性皮疹。他的家族病史中有过敏性皮炎的病史,但他个人没有过敏性皮炎或其他疾病史。他的母亲曾经有湿疹的,并在我们的诊所接受过成功的治疗。
患者的母亲称,患者一个月前接种了COVID-19疫苗第二针。我们无法确定他的湿疹暴发反应是否与COVID-19疫苗有关。检查时,双下肢出现汇合性红斑和丘疹,特别是右侧有结痂和渗出物。他接受了口服中草药和局部中草药乳膏治疗,症状在5个月内缓解。我们感谢患者的家长通过微信发送照片,并同意将这些照片发表。
Reference
- Yu Phuan CZ, Ci-En Choi E, Oon HH. Temporary exacerbation of pre-existing psoriasis and eczema in the context of COVID-19 mRNA booster vaccination: a case report and review of the literature. JAAD Int. 2021;18(6):94–96.
- Leasure AC, Cowper SE, McNiff J, Cohen JM. Generalized eczematous reactions to the Pfizer-BioNTech COVID-19 vaccine. J Eur Acad Dermatol Venereol. 2021 Nov;35(11):e716-e717.
- Corbeddu M, Diociaiuti A, Vinci MR et al. Transient cutaneous manifestations after administration of Pfizer‐BioNTech COVID-19 vaccine: an Italian single centre case series. J Eur Acad Dermatol Venereol 2021; 35: e483–e485.
- Blumenthal KG, Freeman EE, Saff RR et al. Delayed large local reactions to mRNA‐1273 vaccine against SARS-CoV-2. N Engl J Med 2021; 384: 1273–1277.
- McMahon D, Amerson E, Rosenbach M et al. Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: a registry‐based study of 414 case. J Am Acad Dermatol 2021; 85: 46–55.
- Ameri M, Abolmaali M, Alwedaie SMJ, Nabavi M, Rahimian N, Hamidabad NM. Severe Persistent Eczema in a Recipient of the Gam-COVID-Vac vaccine. Eur J Case Rep Intern Med. 2022 Jan 12;9(1):003042.