Central Papillary Atrophy 舌中央乳头状萎缩

Central Papillary Atrophy, also known as Median Rhomboid Glossitis or Erythematous Candidiasis, is found in up to 1% of adults. Central papillary atrophy appears as a well-demarcated, diamond- or oval-shaped area of erythema and atrophy on the dorsum of the tongue, anterior to the circumvallate papillae. The surface may be smooth or lobulated.

It is usually asymptomatic but may also be associated with chronic multifocal candidiasis affecting the palate and angles of the mouth. The mucosal lesion resolves completely or partially after appropriate anticandidal therapy such as clotrimazole troches or oral fluconazole. There is a significant association between Central Papillary Atrophy, Candida and diabetes, but the other possible risk factors, such as gender, smoking and denture, wearing may not be present. Occasionally, immune defects (including HIV) and diabetes predispose to this lesion.

centrealtongue

舌中央乳头状萎缩，又名：正中菱形舌炎或舌红斑念珠菌病，在位于舌背舌周缘乳头前方出现菱形或椭圆形的红斑。1%的成人可出现此症状。它通常是无症状的，但也可能与慢性多灶性念珠菌病有关，影响口腔和口角。在适当的抗念珠菌治疗如克霉唑锭剂或口服氟康唑后，粘膜病变完全或部分消退。中枢性乳头状萎缩与念珠菌和糖尿病之间存在显著关联，但其他可能的风险因素，如性别，吸烟和假牙并不相关。免疫缺陷（包括HIV）和糖尿病偶患这种病变。

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