Surgical site infections are common complications of abdominal surgery. Open abdominal wounds with intestinal fistula formation are challenging complications in abdominal surgery. Many topical agents and alternate therapies are available whom are meant to improve the wound healing environment, however the lack of data is to support any definitive recommendations. Wound dressings should eliminate dead space, control exudate, prevent bacterial overgrowth, ensure proper fluid balance, be cost-efficient, and be manageable for the patient and/or nursing staff. Open label clinical studies of HLQ ointment dressing for sugical wound healing were conducted at Beijing Capital Medical University Hospital. The studies demonstrated that herbal HLQ ointment improve management of these wounds while granulation tissue and epithelialisation can undergo quick closure and coverage. HLQ dressings are changed once daily to avoid disturbing the wound healing environment. During the whole treatment period, local infection was brought under control. The wound was clean, thick granulation tissue formed. The dressing stability provided a high level of patient comfort.
A wound – e.g. Pressure Ulcers, Burns and Heat Injury, Surgical Wound, Mechanical Injury, Chemical Injury, Traumatic Injury – is a disruption of the normal structure and function of the skin and skin architecture . All wounds are colonized with microbes. However, not all wounds are infected [2,3]. Wound healing occurs as a cellular response to tissue injury and involves activation of keratinocytes, fibroblasts, endothelial cells, macrophages, and platelets. The process involves organized cell migration and the recruitment of endothelial cells for angiogenesis. The many growth factors and cytokines released by these cell types coordinate and maintain wound healing. Once hemostasis is achieved, acute wounds normally heal in an orderly and efficient manner characterized by overlapping phases that include inflammation, epithelialization, fibroplasia, and maturation [2-4]. To ensure proper healing, the wound bed needs to be well vascularized, free of devitalized tissue, clear of infection, and moist. By providing expedient wound cleaning, decontamination, local infection control, and patient comfort, as well as helping generate granulation tissue even on biological mesh, HLQ ointment represents a viable tool for the management of challenging fistulizing abdominal wounds.
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