Topical corticosteroids may be associated with cataracts in children as well as adults 类固醇与白内障

The association between systemic corticosteroids and posterior sub-capsular cataracts was first noted by Black et al. Subsequent studies have shown that corticosteroid-induced cataracts may develop following even small doses of steroids, particularly in children. Posterior sub-capsular cataract may occur at a faster rate and lower dosage in children. In addition to systemic steroids, cataracts have also been associated with ocular topical steroids, inhaled steroids and topical steroid creams. When steroids are applied topically to the skin, the degree of systemic absorption depends on factors such as drug potency, the duration of application and whether the skin is thin or damaged. Even low potency steroid creams applied to the eyelids may result in increased intra-ocular pressure and cataract

Cataract extraction in children with atopic cataract can produce excellent visual results, however, it is important to consider the presence of a coexisting retinal detachment. Retinal detachment has been reported in 8% of patients with AD and in one series, 25% of eyes with atopic cataract had retinal breaks or detachment noted pre-operatively.

Andrew Tatham. (2008). Atopic dermatitis, cutaneous steroids and cataracts in children: two case reports. Journal of Medical Case Reports. 2008. 2:124. doi:10.1186/1752-1947-2-124