1. Yufu Cream

• Active Ingredients:
  Taraxacum Mongolicum Extract [1-8], Aloe Vera Extract [9-18], Camellia Sinensis Extract [19-24] , Opuntia Dillenii Extract [25-31], Radix Angelicae Dahuricae Extract [32-36], Houttuynia Cordata Thunb Extract [37-39], Mentha Arvensis Extract [40-49].

2. Lite Balm

• Active Ingredients:
  Camellia Sinensis Extract [19-42], Opuntia Dillenii Extract [25-31], Radix Angelicae Dahuricae Extract [32-36], Mentha Arvensis Extract [40-42].

3. HLQ Ointment

• Active Ingredients:
  Borneolum Syntheticum [43-50], Radix Scutellariae [51-56], Calamine [57].

4. H2 Cream

• Active Ingredients:
  Boswellia sacra [58-65], Commiphora myrrha [66-70], Gypsum, Zinc [71-80], Calamine [57].

To Use:

Apply Over Affected Area.
Moisturises and Protects Skin.
Store Below 30 degree C.

Clinical Evidence

Taraxacum mongolicum [1-8] demonstrates several pharmacological properties relevant to wound healing, including anti-inflammatory, antioxidant, and antimicrobial activities. These effects are attributed to its bioactive constituents such as flavonoids, phenolic acids, sesquiterpene lactones, and polysaccharides, which have been shown to modulate inflammatory pathways (e.g., TLR2-NF-κB/MAPK, PI3K/Akt/mTOR) and enhance antioxidant defenses in preclinical models.

Aloe vera extract [9-18] is supported by both preclinical and clinical evidence as a promoter of wound healing, acting predominantly through anti-inflammatory, antioxidant, and antimicrobial pathways. Its principal bioactive constituents—including acemannan, anthraquinones, and polysaccharides—modulate multiple repair mechanisms: they upregulate growth factors such as TGF-β, VEGF, and IGF-1; stimulate keratinocyte proliferation and migration; enhance extracellular matrix deposition; and regulate inflammatory cytokine activity. Aloe vera also exhibits strong antioxidant capacity, largely mediated by phenolic compounds and polysaccharides, as well as broad-spectrum antimicrobial activity, with demonstrated inhibition of pathogens such as E. coli and S. aureus. Clinical studies and systematic reviews indicate that Aloe vera may accelerate healing in acute wounds and burns, though results for chronic wounds remain inconsistent. Overall, the therapeutic potential is promising, but confirmation requires larger, well-designed trials with standardized preparations and outcome measures.

Camellia sinensis [19-24] extract promotes wound healing through potent anti-inflammatory, antioxidant, and antimicrobial mechanisms, primarily attributed to its polyphenols, especially epigallocatechin gallate (EGCG). EGCG and other catechins modulate key wound healing phases by reducing pro-inflammatory cytokines, scavenging reactive oxygen species (ROS), and enhancing angiogenesis and collagen deposition. In vitro and animal studies demonstrate accelerated wound closure, improved re-epithelialization, increased collagen and fibronectin, and reduced scar formation with topical application of Camellia sinensis extract. Immunomodulatory effects include regulation of hypoxia-responsive microRNAs and dendritic cell signaling, which further support tissue repair and microbial defense.

Opuntia dillenii extract [25-31] bioactive constituents such as polyphenols (quercetin glycosides, vanillic acid, ferulic acid, catechin, rutin), flavonoids, and polysaccharides, demonstrates effectiveness in promoting wound healing, primarily through anti-inflammatory, antioxidant, and antimicrobial mechanisms. In vivo animal models show that Opuntia dillenii extracts accelerate wound contraction, enhance granulation tissue formation, and improve collagen deposition, with histological evidence of reduced inflammation and better tissue organization compared to controls. Anti-inflammatory activity is mediated by inhibition of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6), suppression of arachidonic acid metabolites (COX and LOX pathways), and reduction of eicosanoids (PGE2, LTB4). Opuntiol and opuntioside, isolated from the cladode, are dual inhibitors of COX/LOX and potent suppressors of ROS and cytokine production, comparable to standard anti-inflammatory agents. Antioxidant effects are robust, with strong DPPH and FRAP activity, attributed to high phenolic content, and are correlated with improved wound healing outcomes. Antimicrobial activity is demonstrated against a range of bacteria, supporting its role in infection control during wound repair.

Radix Angelicae Dahuricae [32-36] extract promotes wound healing through multiple mechanisms, including stimulation of angiogenesis, modulation of inflammation, and antimicrobial activity. In diabetic and infected wound models, Angelica dahurica accelerates wound closure by enhancing neovascularization via the HIF-1α/PDGF-β and PI3K/AKT signaling pathways, increasing endothelial cell proliferation, migration, and tube formation, and upregulating angiogenic mediators such as ERK1/2, Akt, and eNOS. It also regulates macrophage polarization, favoring the M2 phenotype, which is associated with resolution of inflammation and tissue repair. Anti-inflammatory effects are mediated by downregulation of pro-inflammatory cytokines (TNF-α, IL-6, IL-1β) and modulation of STAT3 and PTGS2 signaling.[4-5] Antimicrobial activity against Staphylococcus aureus and other pathogens is demonstrated in infected wound models, contributing to reduced bacterial burden and improved healing.

Houttuynia cordata Thunb extract [37-39] demonstrates anti-inflammatory, antioxidant, antimicrobial, and tissue repair properties relevant to wound healing, supported by in vitro, in vivo, and limited clinical data. Its bioactive constituents—volatile oils, flavonoids (afzelin, hyperoside, quercitrin), polysaccharides, and alkaloids—modulate key wound healing pathways. Mechanistically, H. cordata inhibits MAPK signaling, suppresses pro-inflammatory cytokines (TNF-α, IL-1β), and activates the AMPK pathway, resulting in reduced inflammation and oxidative stress, and enhanced fibroblast and keratinocyte function. Polysaccharides from H. cordata further contribute to immune modulation and antibacterial effects, supporting tissue repair and infection control.

Mentha arvensis extract [40-42] contains bioactive compounds including luteolin, rosmarinic acid, oleanolic acid, and ursolic acid, which have been shown in vitro and in silico to inhibit pro-inflammatory cytokines and scavenge free radicals, supporting its potential for reducing skin inflammation and oxidative stress. Antibacterial activity has been demonstrated against pathogens such as Klebsiella pneumoniae and Staphylococcus aureus, suggesting a role in infection control.

Borneolum Syntheticum [43-50] modulates immune function primarily through suppression of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6), inhibition of NF-κB and MAPK signaling pathways, and direct effects on innate immune cells such as neutrophils and macrophages. In vitro and in vivo studies demonstrate that synthetic borneol reduces inflammatory mediator production in LPS-stimulated macrophages and animal models of acute inflammation, leading to decreased tissue edema and inflammatory cell infiltration. Borneol also stabilizes cell membranes and enhances antioxidant defenses by increasing superoxide dismutase activity and reducing malondialdehyde, thereby limiting oxidative stress in the wound microenvironment. Additionally, borneol exhibits immunomodulatory effects on neutrophils, including activation followed by inhibition of chemotaxis and agonist-induced calcium influx, which may help regulate excessive innate immune responses during tissue injury. Its antimicrobial activity is mediated by disruption of bacterial cell walls and synergistic effects with other essential oil components, supporting infection control in wounds and skin disease.

Radix Scutellariae [51-56]plays a significant role in wound healing through potent anti-inflammatory, antioxidant, antimicrobial, and tissue repair mechanisms, primarily attributed to its flavonoids baicalin, baicalein, wogonin, and wogonoside. These compounds suppress pro-inflammatory cytokines (IL-1β, IL-6, TNF-α), inhibit NF-κB, MAPK, and JAK-STAT signaling, and activate Nrf2 and PPAR pathways, resulting in reduced inflammation and oxidative stress, and enhanced fibroblast and keratinocyte function. Scutellaria baicalensis also demonstrates broad-spectrum antimicrobial activity and promotes granulation tissue formation, re-epithelialization, and upregulation of growth factors (VEGF, FGF-2, PDGF-β, CTGF), accelerating wound closure in preclinical models.

Calamine [57] plays a limited role in wound healing, functioning primarily as a skin protectant and antipruritic agent rather than actively promoting tissue repair. Its mechanism is based on the drying of exudative lesions and providing symptomatic relief from itching and minor irritation, as seen in its FDA-approved indications for conditions such as minor cuts, scrapes, insect bites, and rashes. Calamine does not possess significant anti-inflammatory, antioxidant, or antimicrobial properties, nor does it stimulate cell proliferation, migration, or growth factor upregulation relevant to the wound healing cascade.

Boswellia sacra [58-65] plays a significant role in wound healing through its anti-inflammatory, antioxidant, antimicrobial, and tissue repair properties. The resin and its active boswellic acids inhibit pro-inflammatory cytokines (TNF-α, IL-1β, IL-6) and key inflammatory pathways such as NF-κB and 5-lipoxygenase, leading to reduced inflammation and edema at the wound site. Boswellia sacra also demonstrates dose-dependent antioxidant activity, effectively scavenging free radicals and mitigating oxidative stress, which is crucial for optimal wound repair.[6] Its antimicrobial efficacy is notable against Staphylococcus aureus and other wound pathogens, supporting infection control. In tissue repair, Boswellia sacra accelerates wound closure by promoting growth factor expression (e.g., TGF-β, VEGF), enhancing collagen synthesis, and modulating macrophage polarization toward the M2 phenotype, which favors resolution of inflammation and tissue regeneration. These effects have been validated in animal models of acute and diabetic wounds, as well as oral ulcers.

Commiphora myrrha [66-70] plays a multifaceted role in wound healing, with demonstrated anti-inflammatory, antioxidant, antimicrobial, and tissue repair properties. Myrrh resin contains sesquiterpenes, triterpenes, and volatile oils that inhibit pro-inflammatory mediators (e.g., NO, TNF-α, IL-1β), modulate macrophage polarization, and promote fibroblast proliferation and migration, leading to enhanced re-epithelialization and granulation tissue formation. Its extracts—especially ethyl acetate and methanolic fractions—exhibit potent antimicrobial activity against Gram-negative and Gram-positive bacteria, as well as Candida species, and strong radical-scavenging antioxidant effects.In vivo and in vitro studies show myrrh accelerates wound closure and supports immune cell recruitment and differentiation, contributing to effective tissue repair.

Zinc [71-80] is essential for wound healing, acting as a cofactor for numerous enzymes involved in cell proliferation, immune modulation, and extracellular matrix remodeling. Zinc supports keratinocyte migration, collagen synthesis, and angiogenesis, and confers cytoprotection against reactive oxygen species and bacterial toxins via upregulation of metallothioneins and matrix metalloproteinases. Zinc deficiency impairs all phases of wound repair, leading to delayed healing and increased susceptibility to infection. Topical zinc formulations (e.g., zinc oxide, zinc ion-releasing hydrogels, and zinc oxide nanoparticles) provide local anti-inflammatory, antioxidant, and antimicrobial effects, reduce superinfection, and promote autodebridement and epithelialization. Zinc also modulates macrophage polarization and growth factor expression (VEGF, TGF-β, FGF), further accelerating tissue repair.

Reference

1. Updates and Advances on Pharmacological Properties of Taraxacum Mongolicum Hand.-Mazz and Its Potential Applications. Zhang Y, Hu YF, Li W, et al. Food Chemistry. 2022;373(Pt A):131380.
2. Extraction, Purification, Structural Features, Biological Activities, Modifications, and Applications From Taraxacum Mongolicum Polysaccharides: A Review. Liu Y, Shi Y, Zou J, et al. International Journal of Biological Macromolecules. 2024;259(Pt 2):129193.
3. Comparison of Bioactive Phenolic Compounds and Antioxidant Activities of Different Parts of Taraxacum Mongolicum. Duan L, Zhang C, Zhao Y, Chang Y, Guo L. Molecules (Basel, Switzerland). 2020;25(14):E3260. doi:10.3390/molecules25143260.
4. Benzobicyclic Ketones, Cycloheptenone Oxide Derivatives, Guaiane-Type Sesquiterpenes, and Alkaloids Isolated From Taraxacum Mongolicum Hand.-Mazz. Xie J, Wang H, Dong C, et al. Phytochemistry. 2022;201:113277.
5. Taraxacum Mongolicum Protects Against Staphylococcus Aureus-Infected Mastitis by Exerting Anti-Inflammatory Role via TLR2-NF-κB/­MAPKs Pathways in Mice. Ge BJ, Zhao P, Li HT, et al. Journal of Ethnopharmacology. 2021;268:113595.
6. Anti-Inflammatory Effects of Water Extract of Taraxacum Mongolicum Hand.-Mazz on Lipopolysaccharide-Induced Inflammation in Acute Lung Injury by Suppressing PI3K/­Akt/­mTOR Signaling Pathway. Ma C, Zhu L, Wang J, et al. Journal of Ethnopharmacology. 2015;168:349-55.
7. Protective Effects of Organic Acid Component From Taraxacum Mongolicum Hand.-Mazz. Against LPS-induced Inflammation: Regulating the TLR4/­IKK/­NF-κB Signal Pathway. Yang N, Dong Z, Tian G, et al. Journal of Ethnopharmacology. 2016;194:395-402. doi:10.1016/j.jep.2016.08.044.
8. Taraxacum Mongolicum Ameliorates DNCB-Induced Atopic Dermatitis-Like Symptoms in Mice by Regulating Oxidative Stress, Inflammation, MAPK, and JAK/­STAT/­TSLP Signaling Pathways. Jiang WP, Hung HP, Lin JG, et al. International Journal of Molecular Sciences. 2025;26(14):6601. doi:10.3390/ijms26146601.
9. Aloe Vera and the Proliferative Phase of Cutaneous Wound Healing: Status Quo Report on Active Principles, Mechanisms, and Applications. Lee ZM, Goh BH, Khaw KY. Planta Medica. 2025;91(1-02):4-18.
10. Beneficial Effects of the Genus Aloe on Wound Healing, Cell Proliferation, and Differentiation of Epidermal Keratinocytes. Moriyama M, Moriyama H, Uda J, et al. PloS One. 2016;11(10):e0164799.
11. Synergistic Effect of Aloe Vera Flower and Aloe Gel on Cutaneous Wound Healing Targeting MFAP4 and Its Associated Signaling Pathway: In-Vitro Study. Razia S, Park H, Shin E, et al. Journal of Ethnopharmacology. 2022;290:115096.
12. Aloe Polysaccharide Promotes Keratinocyte Proliferation, Migration, and Differentiation by Upregulating the EGFR/­PKC-dependent Signaling Pathways. Cheng CY, Hsu SH, Chokkalingam U, et al. Scientific Reports. 2025;15(1):8196.
13. Topical Application of Aloe Vera Accelerated Wound Healing, Modeling, and Remodeling: An Experimental Study. Oryan A, Mohammadalipour A, Moshiri A, Tabandeh MR. Annals of Plastic Surgery. 2016;77(1):37-46.
14. Oral Administration of Aloe Vera Ameliorates Wound Healing Through Improved Angiogenesis and Chemotaxis in Sprague Dawley Rats. Ali F, Wajid N, Sarwar MG, Qazi AM. Current Pharmaceutical Biotechnology. 2021;22(8):1122-1128.
15. Aloe Vera-Enriched Collagen-Polyurethane Hydrogel: Supporting Tissue Regeneration, Antibacterial Action and Drug Release for Effective Wound Healing. León-Campos MI, Claudio-Rizo JA, Becerra-Rodriguez JJ, et al. Biomedical Materials (Bristol, England). 2025;20(4).
16. Mutagenic, Antioxidant and Wound Healing Properties of Aloe Vera. Rodrigues LLO, de Oliveira ACL, Tabrez S, et al. Journal of Ethnopharmacology. 2018;227:191-197.
17. Aloe Vera for Treating Acute and Chronic Wounds. Dat AD, Poon F, Pham KB, Doust J. The Cochrane Database of Systematic Reviews. 2012;(2):CD008762.
18. The Review on Properties of Aloe Vera in Healing of Cutaneous Wounds. Hashemi SA, Madani SA, Abediankenari S. BioMed Research International. 2015;2015:714216.
19. Beneficial Effects of Green Tea EGCG on Skin Wound Healing: A Comprehensive Review. Xu FW, Lv YL, Zhong YF, et al. Molecules (Basel, Switzerland). 2021;26(20):6123.
20. Effect of Green Tea (Camellia Sinensis) Extract on Healing Process of Surgical Wounds in Rat. Asadi SY, Parsaei P, Karimi M, et al. International Journal of Surgery (London, England). 2013;11(4):332-7.
21. The Effect of Camellia Sinensis on Wound Healing Potential in an Animal Model. Hajiaghaalipour F, Kanthimathi MS, Abdulla MA, Sanusi J. Evidence-Based Complementary and Alternative Medicine : eCAM. 2013;2013:386734.
22. Circulating Hypoxia Responsive microRNAs (HRMs) and Wound Healing Potentials of Green Tea in Diabetic and Nondiabetic Rat Models. Al-Rawaf HA, Gabr SA, Alghadir AH. Evidence-Based Complementary and Alternative Medicine : eCAM. 2019;2019:9019253.
23. ROS Scavenging and Immunoregulative EGCG@Cerium Complex Loaded in Antibacterial Polyethylene Glycol-Chitosan Hydrogel Dressing for Skin Wound Healing. Ye J, Li Q, Zhang Y, et al. Acta Biomaterialia. 2023;166:155-166.
24. Pleiotropic Effects of a Camellia Sinensis Leaf Extract on In vitro and In vivo Skin Health Characteristics. Shill DD, Stade HN, Goodson KC, et al. International Journal of Cosmetic Science. 2025;. doi:10.1111/ics.13073.
25. Antioxidant, Antibacterial and in Vivo Dermal Wound Healing Effects of Opuntia Flower Extracts. Ammar I, Bardaa S, Mzid M, et al. International Journal of Biological Macromolecules. 2015;81:483-90.
26. Characterization of Polyphenolic Compounds From and Their Effects on Wound-Healing Process. Martínez-Cuazitl A, Gómez-García MDC, Hidalgo-Alegria O, et al. Molecules (Basel, Switzerland). 2022;27(19):6521.
27. Extraction, Purification, Structural Features and Biological Activities of the Opuntia Dillenii Polysaccharides: A Review. Li F, Jian Z, Rui Y, Tao A. International Journal of Biological Macromolecules. 2025;314:144253.
28. Opuntia Dillenii Cladode: Opuntiol and Opuntioside Attenuated Cytokines and Eicosanoids Mediated Inflammation. Siddiqui F, Naqvi S, Abidi L, et al. Journal of Ethnopharmacology. 2016;182:221-34.
29. Preliminary Studies of Analgesic and Anti-Inflammatory Properties of Opuntia Dillenii Aqueous Extract. Loro JF, del Rio I, Pérez-Santana L. Journal of Ethnopharmacology. 1999;67(2):213-8.
30. Analyzing the Bioactive Properties and Volatile Profiles Characteristics of Opuntia Dillenii (Ker Gawl.) Haw: Exploring Its Potential for Pharmacological Applications. El Hassania L, Mounime K, Elbouzidi A, et al. Chemistry & Biodiversity. 2024;21(3):e202301890.
31. Exploring the Chemical Profile and Biological Activities of Opuntia Dillenii Extracts and Seed Oil. Elouazkiti M, Elyacoubi H, Gadhi C, Bouamama H, Rochdi A. Natural Product Research. 2025;:1-11.
32. Angelica Dahurica Promoted Angiogenesis and Accelerated Wound Healing in Db/­Db Mice via the HIF-1α/­PDGF-β Signaling Pathway. Guo J, Hu Z, Yan F, et al. Free Radical Biology & Medicine. 2020;160:447-457.
33. Angelica Dahurica Ethanolic Extract Improves Impaired Wound Healing by Activating Angiogenesis in Diabetes. Zhang XN, Ma ZJ, Wang Y, et al. PloS One. 2017;12(5):e0177862.
34. Proteomics and Transcriptomics Explore the Effect of Mixture of Herbal Extract on Diabetic Wound Healing Process. Liu Y, Zhang X, Yang L, et al. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 2023;116:154892.
35. Angelica Dahurica Regulated the Polarization of Macrophages and Accelerated Wound Healing in Diabetes: A Network Pharmacology Study and Experimental Validation. Hu Y, Lei S, Yan Z, et al. Frontiers in Pharmacology. 2021;12:678713.
36. Antimicrobial and Anti-Inflammatory Potential of Angelica Dahurica and Rheum Officinale Extract Accelerates Wound Healing in Staphylococcus Aureus-Infected Wounds. Yang WT, Ke CY, Wu WT, Tseng YH, Lee RP. Scientific Reports. 2020;10(1):5596.
37. Therapeutic Potentials of Houttuynia Cordata Thunb. Against Inflammation and Oxidative Stress: A Review. Shingnaisui K, Dey T, Manna P, Kalita J. Journal of Ethnopharmacology. 2018;220:35-43.
38. Houttuynia Cordata Thunb.: A Comprehensive Review of Traditional Applications, Phytochemistry, Pharmacology and Safety. Wei P, Luo Q, Hou Y, et al. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 2024;123:155195.
39. Unveiling Polysaccharides of Houttuynia Cordata Thunb.: Extraction, Purification, Structure, Bioactivities, and Structure-Activity Relationships. Gao S, Wang W, Li J, et al. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 2025;138:156436.
40. The Wonderful Activities of the Genus Mentha: Not Only Antioxidant Properties. Tafrihi M, Imran M, Tufail T, et al. Molecules (Basel, Switzerland). 2021;26(4):1118.
41. Exploring the Antibacterial, Antidiabetic, and Anticancer Potential of Mentha Arvensis Extract Through in-Silico and in-Vitro Analysis. Faisal S, Tariq MH, Ullah R, et al. BMC Complementary Medicine and Therapies. 2023;23(1):267.
42. Ethanolic Extraction and GC-MS Analysis of Antioxidant and Anticancer Bioactive Compounds From Mentha Arvensis and Aegle Marmelos. Mathai RV, Sar SK, Mitra JC, Jindal MK, Wang F. Natural Product Research. 2024;:1-7.
43. Advances and Perspectives on Pharmacological Activities and Mechanisms of the Monoterpene Borneol. Hu X, Yan Y, Liu W, et al. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 2024;132:155848.
44. Comparison of Chemical Profiles, Anti-Inflammatory Activity, and UPLC-Q-TOF/­MS-Based Metabolomics in Endotoxic Fever Rats Between Synthetic Borneol and Natural Borneol. Zou L, Zhang Y, Li W, et al. Molecules (Basel, Switzerland). 2017;22(9):E1446.
45. The Antibacterial and Anti-Inflammatory Potential of Cinnamomum Camphora Chvar. Borneol Essential Oil in Vitro. Xiao S, Yu H, Guo Y, Cheng Y, Yao W. Plants (Basel, Switzerland). 2025;14(12):1880.
46. Analgesic and Anti-Inflammatory Effects and Mechanism of Action of Borneol on Photodynamic Therapy of Acne. Ji J, Zhang R, Li H, et al. Environmental Toxicology and Pharmacology. 2020;75:103329.
47. Modulation of LPS-stimulated Pulmonary Inflammation by Borneol in Murine Acute Lung Injury Model. Zhong W, Cui Y, Yu Q, et al. Inflammation. 2014;37(4):1148-57.
48. L-Borneol Promotes Skin Flap Survival by Regulating HIF-1α/­NF-κB Pathway. Chen G, Yang J, Wang A, et al. Journal of Ethnopharmacology. 2023;321:117543.
49. Neutrophil Immunomodulatory Activity of (-)-Borneol, a Major Component of Essential Oils Extracted From . Schepetkin IA, Özek G, Özek T, et al. Molecules (Basel, Switzerland). 2022;27(15):4897.
50. All-Natural Injectable Antibacterial Hydrogel Enabled by Chitosan and Borneol. Zhao Z, Fan X, Li X, et al. Biomacromolecules. 2023;. doi:10.1021/acs.biomac.3c00874.
51. The Main Bioactive Compounds of Scutellaria Baicalensis Georgi. For Alleviation of Inflammatory Cytokines: A Comprehensive Review. Liao H, Ye J, Gao L, Liu Y. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 2021;133:110917.
52. Recent Advances in Scutellariae Radix: A Comprehensive Review on Ethnobotanical Uses, Processing, Phytochemistry, Pharmacological Effects, Quality Control and Influence Factors of Biosynthesis. Ma W, Liu T, Ogaji OD, et al. Heliyon. 2024;10(16):e36146.
53. Scutellaria Baicalensis Georgi. (Lamiaceae): A Review of Its Traditional Uses, Botany, Phytochemistry, Pharmacology and Toxicology. Zhao T, Tang H, Xie L, et al. The Journal of Pharmacy and Pharmacology. 2019;71(9):1353-1369.
54. Effect of Baicalin on Wound Healing in a Mouse Model of Pressure Ulcers. Kim E, Ham S, Jung BK, et al. International Journal of Molecular Sciences. 2022;24(1):329.
55. Efficacy Identification and Active Compounds Screening of Topically Administration of Scutellaria Radix in Oral Ulcer. Luo H, Yu Y, Liang M, et al. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 2023;1215:123571.
56. Production of Bacterial Cellulose With High Active Components Loading Capacity for Skin Wound Repair. Xu J, Wang Q, Hu Y, et al. International Journal of Biological Macromolecules. 2025;311(Pt 3):143963.
57. calahist. FDA Drug Label. Food and Drug Administration Updated date: 2023-10-27
58. Alpha-Boswellic Acid Accelerates Acute Wound Healing via NF-κB Signaling Pathway. Dong F, Zheng L, Zhang X. PloS One. 2024;19(9):e0308028. doi:10.1371/journal.pone.0308028.
59. Anti-Inflammatory Properties of Boswellia Frereana Birdw., Boswellia Neglecta S.Moore, Boswellia Rivae Engl., Boswellia Sacra Flück., Boswellia Serrata Roxb., Commiphora Confusa Vollesen, Commiphora Kataf (Forssk.) Engl. And Commiphora Myrrha (T.Nees) Engl. Extracts in Viral and Chronic Respiratory Inflammation. Stengler E, Huber R, Kowarschik S, Lüth VM. Journal of Ethnopharmacology. 2025;354:120500.
60. Boswellic Acids in Chronic Inflammatory Diseases. Ammon HP. Planta Medica. 2006;72(12):1100-16.
61. Boswellia Serrata, a Potential Antiinflammatory Agent: An Overview. Siddiqui MZ. Indian Journal of Pharmaceutical Sciences. 2011;73(3):255-61.
62. Boswellia Serrata: An Overall Assessment of in Vitro, Preclinical, Pharmacokinetic and Clinical Data. Abdel-Tawab M, Werz O, Schubert-Zsilavecz M. Clinical Pharmacokinetics. 2011;50(6):349-69.
63. Antimicrobial and Antioxidant Properties of Boswellia Sacra Resin: Extraction, Evaluation, and Formulation Into a Topical Cream for Dermatological Applications. Al-Saban A, Maad AH, Al-Sham AS, Saad HM. Frontiers in Medicine. 2025;12:1664265.
64. Boswellia Extract Promotes Healing and Resolving Inflammation in Oral Ulcers of Rat. Zhao W, Jia Z, Han J, Sun X. Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. 2025;54(3):131-140
65. Wound Healing Potential of the Standardized Extract of Boswellia Serrata on Experimental Diabetic Foot Ulcer via Inhibition of Inflammatory, Angiogenetic and Apoptotic Markers. Pengzong Z, Yuanmin L, Xiaoming X, et al. Planta Medica. 2019;85(8):657-669. doi:10.1055/a-0881-3000.
66. Elucidation and Valorization of the Potent Activity of Commiphora Myrrha Gum Resin Extract: Antimicrobial and Fibroblast Wound Healing Activities. Khalil RM, Ghanem NB, Khairy H. Scientific Reports. 2025;15(1):31839.
67. Commiphora Myrrh: A Phytochemical and Pharmacological Update. Batiha GE, Wasef L, Teibo JO, et al. Naunyn-Schmiedeberg’s Archives of Pharmacology. 2023;396(3):405-420.
68. The Role of Myrrh Metabolites in Cancer, Inflammation, and Wound Healing: Prospects for a Multi-Targeted Drug Therapy. Suliman RS, Alghamdi SS, Ali R, et al. Pharmaceuticals (Basel, Switzerland). 2022;15(8):944.
69. An Unprecedented 4,8-Cycloeudesmane, Further New Sesquiterpenoids, a Triterpene, Steroids, and a Lignan From the Resin of Commiphora Myrrha and Their Anti-Inflammatory Activity in Vitro. Unterholzner A, Kuck K, Weinzierl A, Lipowicz B, Heilmann J. Molecules (Basel, Switzerland). 2024;29(18):4315.
70. Effect of Commiphora Molmol on Leukocytes Proliferation in Relation to Histological Alterations Before and During Healing From Injury. Haffor AS. Saudi Journal of Biological Sciences. 2010;17(2):139-46.
71. Zinc in Wound Healing Modulation. Lin PH, Sermersheim M, Li H, et al. Nutrients. 2017;10(1):E16.
72. Zinc in Wound Healing: Theoretical, Experimental, and Clinical Aspects. Lansdown AB, Mirastschijski U, Stubbs N, Scanlon E, Agren MS. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [And] the European Tissue Repair Society. 2007 Jan-Feb;15(1):2-16.
73. Chondroitin Sulfate Zinc With Antibacterial Properties and Anti-Inflammatory Effects for Skin Wound Healing. Wu G, Ma F, Xue Y, et al. Carbohydrate Polymers. 2022;278:118996.
74. Biocompatible, Antibacterial and Anti-Inflammatory Zinc Ion Cross-Linked Quaternized Cellulose‑sodium Alginate Composite Sponges for Accelerated Wound Healing. Xie H, Xia H, Huang L, et al. International Journal of Biological Macromolecules. 2021;191:27-39.
75. Zinc-Mineralized Diatom Biosilica/­Hydroxybutyl Chitosan Composite Hydrogel for Diabetic Chronic Wound Healing. Ding Y, Mu Y, Hu Y, et al. Journal of Colloid and Interface Science. 2024;656:1-14.
76. Tight Orchestration of Wound Healing Phase Through Metal-Organic Compounds. Wang R, Li X, Wang C, et al. Biomaterials. 2025;318:123160.
77. Exploration of the Antibacterial and Wound Healing Potential of a PLGA/­silk Fibroin Based Electrospun Membrane Loaded With Zinc Oxide Nanoparticles. Khan AUR, Huang K, Jinzhong Z, et al. Journal of Materials Chemistry. B. 2021;9(5):1452-1465.
78. Zinc Ions Coordinated Carboxymethyl Chitosan Hydrogel Doped With Ellagic Acid for Accelerative Diabetic Wound Healing. Zhao J, Du J, Zheng Y, et al. International Journal of Biological Macromolecules. 2025;:147372.
79. Antibacterial and Antioxidative Hydrogel Dressings Based on Tannic Acid-Gelatin/­Oxidized Sodium Alginate Loaded With Zinc Oxide Nanoparticles for Promoting Wound Healing. Liu H, Yang Y, Deng L, et al. International Journal of Biological Macromolecules. 2024;279(Pt 2):135177.
80. Preparation and Evaluation of a Novel Alginate-Arginine-Zinc Ion Hydrogel Film for Skin Wound Healing. Mao G, Tian S, Shi Y, et al. Carbohydrate Polymers. 2023;311:120757.