Relapse Rate in the Real World Following Biologic Discontinuation in Psoriasis 真实世界中生物制剂停药后银屑病复发率
Across three of the four studies, roughly 8–9 out of 10 patients flared again after stopping their biologic. Even the IL-23 group, which many doctors think is longer-lasting, showed most relapses within a year. One study that mixed mainly IL-17 drugs saw a lower figure (about 1 in 2 relapsed by 6 months), but the authors only tracked that 6-month window, so the final total would likely be higher. Bottom line: biologics control psoriasis well while you take them, but stopping usually leads to a comeback fairly quickly.
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