Treating vitiligo with herb medicine 植物中药治疗白癜风

Vitiligo is an acquired disorder characterized by circumscribed depigmented macules and patches that result from the loss of functional melanocytes. Although patients with vitiligo may attribute the onset of their disease to specific life events (e.g. physical injury, sunburn, emotional distress, illness, pregnancy), with the exception of the Koebner phenomenon, there is no proof that these factors cause or precipitate vitiligo.

vitiligo a1

Uveitis is the most significant ocular abnormality associated with vitiligo. Autoimmune thyroid disease occurs in ~15% of adults and ~5–10% of children with vitiligo, and other less frequently associated conditions include pernicious anemia, Addison disease, lupus erythematosus, rheumatoid arthritis, and adult-onset insulin-dependent diabetes mellitus. Of note, these conditions have been linked to the same autoimmunity predisposition genes as in vitiligo (e.g. PTPN22, NLRP1). Halo melanocytic nevi, alopecia areata, and lichen sclerosus are additional autoimmune skin conditions that may be associated with vitiligo.

vitiligo b1

Conventional treatment used as same as for psoriasis, eczema, eg. corticosteroids, topical calcineurin inhibitors (tacrolimus or pimecrolimus), Narrowband UVB, Psoralen+UVA. We introduced herbal medicine TCM to manage the vitiligo.

白癜风是一种功能性黑素细胞丧失引起的局限性脱色斑和斑为主要表现的获得性、色素障碍性疾病。虽然白癜风患者可能将其疾病的发作归因于特定的生活事件（例如物理损伤，晒伤，情绪困扰，疾病，怀孕），但除Koebner现象外，没有证据表明这些因素会导致白癜风。

葡萄膜炎是与白癜风相关的最显着的眼部异常。 自身免疫性甲状腺疾病发生在~15％的成人和约5-10％的白癜风儿童中，其他不太常见的相关疾病包括恶性贫血，艾迪生病，红斑狼疮，类风湿性关节炎和成人发病的胰岛素依赖型糖尿病。 值得注意的是，这些病症与白癜风中相同的自身免疫易感基因有关（例如PTPN22，NLRP1）。 Halo黑色素细胞痣，斑秃和硬化性苔藓是可能与白癜风有关的其他自身免疫性皮肤病。

治疗白癜风的常规方法与治疗牛皮癣，湿疹相同，例如： 皮质类固醇，局部钙调神经磷酸酶抑制剂（他克莫司或吡美莫司），窄带UVB，补骨脂素+ UVA。 此处附件我们介绍植物中药来治疗白癜风的状况。

Reference:

  1. Antonella Tosti, Bianca Maria Piraccini. In: Jean Bolognia Julie Schaffer Lorenzo Cerroni, editors. Dermatology: 2-Volume Set 4th Edition. Elsevier; 2017. p1087-1114
  2. C Vrijman, MW Kroon, J Limpens, et al.: The prevalence of thyroid disease in patients with vitiligo: a systematic review. Br J Dermatol. 167:1224-1235 2012 22860695
  3. A Alkhateeb, PR Fain, A Thody, et al.: Epidemiology of vitiligo and associated autoimmune diseases in Caucasian probands and their families. Pigment Cell Res. 16:208-214 2003 12753387
  4. G Laberge, CM Mailloux, K Gowan, et al.: Early disease onset and increased risk of other autoimmune diseases in familial generalized vitiligo. Pigment Cell Res. 18:300-305 2005 1602942
  5. Zhu ML, A Nagavalli, Su MA: Aire deficiency promotes TRP-1-specific immune rejection of melanoma. Cancer Res. 73:2104-2116 2013 23370329